What is HY-50 Vet 17 mg/ml Sodium Hyaluronate Inj 3ml?
- HY-50 Vet is a sodium hyaluronate (hyaluronic acid, HA) injection, supplied at a concentration of 17 mg/mL in a 3 mL syringe, delivering 51 mg of HA per dose.
- It is licensed for both intra-articular and intravenous use in horses experiencing lameness caused by joint dysfunction associated with non-infectious synovitis.
- Sodium hyaluronate is a naturally occurring biopolymer found throughout animal connective tissue.
- It’s a key component of synovial fluid and articular cartilage, where it acts as a natural lubricant and cushioning agent for the joint. HY-50 Vet is manufactured through a fermentation process that delivers exceptionally high purity, making it suitable for direct joint and intravenous administration.
Why Choose HY-50 Vet
Compared to many other hyaluronate products on the market, HY-50 Vet stands out for two key reasons:
- Higher concentration per dose — at 17 mg/mL, HY-50 Vet delivers a greater amount of hyaluronic acid in a smaller injection volume compared to standard 10 mg/mL products
- High molecular weight — supporting stronger viscoelastic (cushioning and lubricating) properties within the joint
These qualities allow HY-50 Vet to more effectively restore the natural thickness and lubricating quality of synovial fluid, helping the joint move more comfortably.
How HY-50 Vet Works
When injected into the joint or bloodstream, sodium hyaluronate:
- Enhances the viscoelasticity (cushioning ability) of synovial fluid
- Supports the natural tissue-repair process in joint cartilage
- Helps reduce inflammation within the joint
- Provides pain relief associated with joint dysfunction
- Acts as an antioxidant within the joint environment
Independent research using an equine lameness model found that intravenous HY-50 produced substantial improvement in lameness score, stride length, and joint flexion within the first few weeks of treatment, with continued improvement over 33 days.
Dosage and Administration
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Intravenous use:
- One 3 mL syringe, administered once weekly, for three consecutive weeks. This route is often preferred when more than one joint is affected, or when direct joint injection isn’t appropriate.
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Intra-articular use:
- Medium and large joints: 3 mL (51 mg) per joint, single dose
- Small joints (e.g., intertarsal): 1.5 mL (25.5 mg), half a syringe
- More than one joint may be treated in the same session. Excess synovial fluid should be drawn off before injection, where possible.
Administration Guidelines
- Bring the syringe to room temperature approximately 10 minutes before use
- Administer under strict aseptic conditions
- Ensure the injection site is free of dirt, hair, and antiseptic residue
- Do not inject through skin that is infected, blistered, or otherwise compromised
- Apply a sterile dressing and clean bandage after injection, as appropriate to the joint treated
Prescription Requirement
- HY-50 Vet is available by veterinary prescription only and must be administered by, or under the direct supervision of, a licensed veterinarian.
Why Choose Wadi Alhgn Veterinary Medicines for HY-50 Vet
- At Wadi Alhgn Veterinary Medicines, every vial of HY-50 Vet is sourced through authentic, verified supply channels.
- Under the guidance of Founder & CEO Dr. Sameh Ali, a specialist in intra-articular and intravenous joint injection therapy, our team ensures correct cold-chain handling and full traceability, so veterinarians can trust the product’s purity and potency from delivery to administration.

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